Livgran Infusion

What is Livgran Infusion

Livgran Infusion is a prescription hepatoprotective medication containing L-Ornithine L-Aspartate (5 gm per 10 ml). Formulated as a concentrated solution for intravenous drip infusion, Livgran is primarily used to treat severe liver diseases, hepatic encephalopathy, and high toxic ammonia levels in the blood.

Key Ingredients & Their Role

Livgran Infusion contains the following active component:

• L-Ornithine L-Aspartate (5 gm / 10 ml):

  • Ammonia Detoxification: Combines two key amino acids (ornithine and aspartate) that stimulate the urea cycle and glutamine synthesis, effectively converting toxic ammonia into non-toxic urea for excretion.

  • Hepatic Cell Protection: Promotes cellular energy production and supports liver tissue regeneration in damaged or failing livers.

Benefits & What It Helps With

Using Livgran Infusion can help with:

• Management of Hepatic Encephalopathy: Reduces blood ammonia levels to alleviate brain dysfunction, confusion, and altered consciousness caused by severe liver failure.

• Support in Chronic Liver Diseases: Protects liver tissue in conditions such as liver cirrhosis, chronic hepatitis, and severe fatty liver disease.

• Rapid Ammonia Clearance: Provides fast-acting intravenous detoxification for hospitalized patients experiencing acute hyperammonemia.

Who Should Use Livgran Infusion

This prescription medication is generally indicated for:

• Hospitalized patients diagnosed with Hepatic Encephalopathy or elevated blood ammonia levels.

• Individuals with advanced liver cirrhosis or severe chronic liver damage needing acute medical intervention.

Important: Livgran Infusion is a potent prescription drug (marked Rx) and must be administered strictly in a clinical setting under medical supervision.

How to Use & Dosage Advice

• Administration Route: For I.V. Slow Drip Infusion Only. The concentrate must be diluted in an appropriate infusion solution (e.g., normal saline or dextrose solution) prior to administration.

• Dosage & Rate: The exact dose, dilution ratio, and infusion speed are determined strictly by the treating gastroenterologist, hepatologist, or critical care physician based on the patient’s condition.

• Hospital Setting: Must be given by a trained healthcare professional; do not attempt to self-administer.

Precautions & When to Avoid

• Avoid using if you have severe renal insufficiency or kidney failure (e.g., serum creatinine levels significantly above normal).

• Contraindicated in patients with known hypersensitivity to L-Ornithine L-Aspartate or any constituents.

• Infusion rate must be kept slow to avoid nausea, vomiting, or local vascular irritation.

• Pregnant or breastfeeding women should consult a specialist prior to treatment.

Storage & Handling

• Store in a cool, dry place protected from direct light, heat, and moisture.

• Do not freeze.

• Keep out of reach of children.

• Packaging: 1 x 10 ml ampoule packaging (Infusion concentrate for slow I.V. drip).

• Always check the solution for clarity and verify the expiry date prior to administration.