Graxamide ER 300

What is Graxamide ER 300

Graxamide ER 300 Tablets is a prescription prokinetic medication containing Acotiamide Hydrochloride Hydrate Extended Release (300 mg). It is formulated to manage gastrointestinal motility disorders and provide targeted relief from functional dyspepsia symptoms like postprandial fullness, early satiety, and upper abdominal bloating.

Key Ingredients & Their Role

Graxamide ER 300 contains the following active component:

• Acotiamide Hydrochloride Hydrate (300 mg – Extended Release):

  • Acetylcholinesterase (AChE) Inhibitor: Inhibits the enzyme acetylcholinesterase, preventing the breakdown of acetylcholine in the gastrointestinal tract.

  • Enhanced Gastric Motility: Increases acetylcholine levels to stimulate stomach contractions, improve delayed gastric emptying, and enhance gastric accommodation during meals.

  • Extended Release (ER) Formulation: Delivers controlled release of the active drug to allow convenient dosing while sustaining therapeutic levels throughout the day.

Benefits & What It Helps With

Using Graxamide ER 300 Tablets can help with:

• Postprandial Distress Syndrome (PDS): Relieves unpleasant fullness and discomfort after eating meals.

• Early Satiety: Prevents the sensation of feeling prematurely full shortly after beginning a meal.

• Upper Abdominal Bloating & Discomfort: Facilitates smoother stomach motility to reduce bloating, heaviness, and upper abdominal pain.

• Improved Gastric Emptying: Helps move food more efficiently from the stomach into the small intestine.

Who Should Use Graxamide ER 300

This prescription medicine is generally indicated for:

• Patients diagnosed with Functional Dyspepsia suffering from meal-related symptoms (postprandial fullness, early satiation, bloating).

• Individuals with delayed gastric motility needing prokinetic support.

Important: Graxamide ER 300 is a prescription medication (marked Rx) and must strictly be taken under the supervision of a gastroenterologist or physician.

How to Use & Dosage Advice

• Administration: Swallow the tablet whole with a glass of water. Do not crush, split, or chew extended-release tablets, as this can break the controlled-release mechanism.

• Timing: Generally taken before meals (as advised by your physician) to maximize its effect on digestion and gastric motility.

• Dosage: Follow the exact dosage and duration prescribed by your doctor.

Precautions & When to Avoid

• Avoid using if you have a known hypersensitivity or allergy to Acotiamide or any inactive ingredients in the tablet.

• Contraindicated in cases where gastrointestinal stimulation could be dangerous (such as gastrointestinal hemorrhage, mechanical obstruction, or perforation).

• Use with caution in patients with hepatic or renal impairment.

• Pregnant or breastfeeding women should consult a specialist before initiating treatment.

• Common side effects are generally mild but may include diarrhea, constipation, nausea, elevated liver enzymes, or headache.

Storage & Handling

• Store in a cool, dry place away from direct light, heat, and moisture.

• Keep out of reach of children.

• Packaging: 10×10 Alu Alu blister packaging (10 tablets per strip).

• Always check the expiry date on the packaging prior to use.