Pregshape 500

What is Pregshape 500 Injection

Pregshape 500 Injection is a prescription hormonal medication containing Hydroxyprogesterone Caproate I.P. (500 mg per 2 ml). It is a synthetic progestin (progesterone derivative) formulated primarily to maintain pregnancy support, reduce the risk of preterm (premature) labor in pregnant women, and manage progesterone deficiency disorders like habitual or recurrent miscarriage.

Key Ingredients & Their Role

Pregshape 500 contains the following active component:

• Hydroxyprogesterone Caproate I.P. (500 mg / 2 ml):

  • Synthetic Progestin: Mimics natural progesterone, a vital female hormone essential for sustaining a healthy uterine lining (endometrium).

  • Uterine Muscle Relaxation: Relaxes uterine smooth muscle tissue to reduce uterine contractions and maintain uterine quiescence during pregnancy.

  • Pregnancy Maintenance: Supports placental attachment and prevents early cervical shortening or thinning, helping carry the pregnancy to term.

Benefits & What It Helps With

Using Pregshape 500 Injection can help with:

• Prevention of Preterm Labor: Reduces the incidence of premature delivery in women with a history of spontaneous preterm birth.

• Prevention of Recurrent Miscarriage: Helps maintain pregnancy in women experiencing habitual or threatened miscarriage caused by luteal phase deficiency.

• Support in Assisted Reproductive Technology (ART): Supplementation of progesterone in fertility treatments and early pregnancy support.

• Management of Gynecological Disorders: Used off-label or in specialized protocols for dysfunctional uterine bleeding, amenorrhea, or endometriosis management as prescribed by a gynecologist.

Who Should Use Pregshape 500 Injection

This prescription medication is generally indicated for:

• Pregnant women with a documented history of spontaneous singleton preterm birth.

• Women presenting with threatened or recurrent miscarriage attributed to endogenous progesterone deficiency.

Important: Pregshape 500 is a potent hormonal prescription drug (marked Rx) and must be administered strictly under the supervision of a qualified obstetrician or gynecologist.

How to Use & Dosage Advice

• Administration Route: For Intramuscular (I.M.) use only. Should be injected deep into the gluteal muscle (buttock) by a trained healthcare professional.

• Dosage & Schedule: Dosing frequency (e.g., weekly or bi-weekly injections) is determined strictly by the treating obstetrician based on pregnancy stage and clinical need.

• Self-Administration Warning: Do not attempt to self-inject. Always visit a clinic, hospital, or trained nurse for administration.

Precautions & When to Avoid

• Avoid using if you have a known hypersensitivity or allergy to Hydroxyprogesterone Caproate, castor oil, or any constituents of the injection.

• Contraindicated in conditions like active liver disease, hepatic tumors, uncontrolled hypertension, history of thromboembolic events (blood clots or stroke), or undiagnosed abnormal vaginal bleeding.

• Not indicated for multiple gestations (e.g., twins or triplets) unless specifically directed by a specialist.

• Common mild side effects at the injection site include local swelling, pain, itching, redness, or mild nodule formation.

Storage & Handling

• Store in a cool, dry place protected from direct light, heat, and moisture.

• Do not freeze.

• Keep out of reach of children.

• Packaging: Box contains 1 x 2 ml ampoule along with a sterile disposable syringe.

• Always verify the clarity of the solution and expiry date prior to administration.