Sezifura-3 Kit

Sezifura-3 Kit Tablets – Combipack of Azithromycin, Fluconazole & Secnidazole Tablets

When mixed syndromic pelvic and genital infections require comprehensive multi-pathogen coverage, Sezifura-3 Kit by Grantham Lifesciences provides a conveniently packaged, single-day oral combipack. Each blister kit contains four tablets featuring three complementary therapeutic agents: Azithromycin Dihydrate IP equivalent to Azithromycin 1 g (1 tablet), Fluconazole IP 150 mg (1 tablet), and Secnidazole IP 1 g (2 tablets). Designed for convenient administration under professional medical direction, this combipack provides targeted antibacterial, antifungal, and antiprotozoal action.

Why Sezifura-3 Kit Stands Out:

• Triple-Action Combipack Formulation: Combines Azithromycin 1 g (antibacterial), Fluconazole 150 mg (antifungal), and Secnidazole 1 g x 2 (antiprotozoal/anti-anaerobic) in a single convenient strip.

• Syndromic Treatment Approach: Designed for the comprehensive management of vaginal discharge syndrome, syndromic pelvic inflammatory disease (PID), and mixed genital tract infections.

• Clear Compliance Packaging: The blister pack is clearly marked with dosing times (e.g., After Breakfast, Before Lunch, After Dinner) to ensure optimal therapeutic compliance.

• Convenient Presentation: Packaged as a 10x1x4 Blister (4 tablets per kit blister in a box of 10 kits).

• Marketed by Grantham Lifesciences: Formulated and distributed under strict pharmaceutical quality standards.

Uses & Indications

Sezifura-3 Kit may be prescribed for the syndromic treatment of mixed lower genital tract infections, including:

• Vaginal Discharge Syndrome: Comprehensive coverage for bacterial vaginosis, vulvovaginal candidiasis, and trichomoniasis.

• Pelvic Inflammatory Disease (PID): Co-management of syndromic pelvic infections involving polymicrobial pathogens.

• Sexually Transmitted Infections (STIs): Effective against common STI pathogens including Chlamydia trachomatis, Neisseria gonorrhoeae, Candida albicans, and Trichomonas vaginalis.

• Urethritis / Cervicitis: Mixed infectious conditions affecting the lower genitourinary tract.

Key Benefits

• Broad-Spectrum Multi-Pathogen Coverage: Eliminates bacteria, yeasts, and protozoa simultaneously without needing separate prescriptions.

• Enhanced Patient Compliance: Blister sequence clearly guides the patient through the exact administration schedule across the day.

• Single-Day Complete Course: Offers rapid syndromic resolution, minimizing the burden of multi-day dosage regimens.

• Partner Treatment Option: Ideal for simultaneous treatment of sexual partners when indicated by healthcare guidelines.

Dosage & Administration

• Sezifura-3 Kit must be taken strictly as prescribed by a Registered Medical Practitioner.

• Standard Dosing Schedule (as indicated on the blister packaging):

  • Morning (After Breakfast): Take 1 tablet of Fluconazole 150 mg.

  • Midday (1 Hour Before Lunch): Take 1 tablet of Azithromycin 1 g.

  • Evening (After Dinner): Take 2 tablets of Secnidazole 1 g together.

• Directions:

  • Swallow each tablet whole with a glass of water.

  • Do not crush, chew, or break the tablets.

  • Avoid alcohol consumption during and for at least 48 hours after taking the Secnidazole dose to prevent disulfiram-like reactions.

Possible Side Effects

Sezifura-3 Kit is generally well tolerated, though temporary mild side effects may occur:

• Metallic taste or altered taste sensation (commonly associated with Secnidazole)

• Nausea, vomiting, or abdominal pain

• Diarrhea or loose stools

• Headache or dizziness

• Mild skin rash or itching

Contact a doctor immediately if severe persistent vomiting, skin rash, or signs of an allergic reaction occur.

Precautions & Interactions

• Alcohol Restriction: Avoid all forms of alcohol during treatment and for 48 hours afterward to prevent severe nausea, flushing, or abdominal cramps.

• Pregnancy & Lactation: Should be used during pregnancy or breastfeeding only if clearly indicated and specifically prescribed by an obstetrician/gynecologist.

• Hypersensitivity: Contraindicated in patients with known hypersensitivity to macrolides (azithromycin), azoles (fluconazole), or nitroimidazoles (secnidazole).

• Prescription Medicine: This is a Schedule H Prescription Drug — to be sold by retail on the prescription of a Registered Medical Practitioner only.

Storage Instructions

• Store protected from light and moisture in a cool, dry place.

• Keep out of reach of children.

• Keep the tablets inside the original blister card until consumption.

• Do not use beyond the printed expiration date.

Packaging & Product Information

• Product Name: Sezifura-3 Kit Tablets

• Marketed by: Grantham Lifesciences

• Dosage Form: Oral Combipack (Tablets)

• Compositions (4 Tablets per Kit):

  • Fluconazole IP: 150 mg (1 Tablet)

  • Azithromycin Dihydrate IP eq. to Azithromycin: 1 g (1 Tablet)

  • Secnidazole IP: 1 g (2 Tablets)

• Category: Antifungal, Antibacterial & Antiprotozoal Combipack

• Route of Administration: Oral Use

• Pack Size: 10x1x4 Blister (1 Strip = 1 Kit = 4 Tablets)

• MRP: ₹160/- per kit

• GST: 5%

Frequently Asked Questions (FAQs)

Q1. What is Sezifura-3 Kit used for?

A. Sezifura-3 Kit is a combipack used for the syndromic treatment of mixed vaginal and pelvic infections, including vaginal discharge caused by fungal, bacterial, and protozoal pathogens.

Q2. What tablets are contained in the Sezifura-3 Kit?

A. Each kit strip contains 4 tablets: 1 tablet of Fluconazole 150 mg, 1 tablet of Azithromycin 1 g, and 2 tablets of Secnidazole 1 g.

Q3. How should I take the tablets in the Sezifura-3 Kit?

A. Follow the schedule printed on the blister card: Take Fluconazole after breakfast, Azithromycin 1 hour before lunch, and the two Secnidazole tablets together after dinner, or as explicitly directed by your physician.

Q4. Can I consume alcohol while taking Sezifura-3 Kit?

A. No. You must strictly avoid alcohol while taking this kit and for at least 48 hours after completing it to avoid severe adverse interactions with Secnidazole.

Q5. Can both sexual partners take this kit?

A. In many cases of sexually transmitted or recurrent vaginal infections, doctors recommend treating both partners simultaneously to prevent reinfection. Consult your doctor for appropriate guidance.

Q6. Is Sezifura-3 Kit available without a prescription?

A. No. Sezifura-3 Kit is a Schedule H prescription medicine and must be taken under the supervision of a registered medical practitioner.